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Yoshinobu Horiuchi Selected Research

Combined Vaccines

9/2014A national reference for inactivated polio vaccine derived from Sabin strains in Japan.
1/2014Investigation in a murine model of possible mechanisms of enhanced local reactions to post-primary diphtheria-tetanus toxoid boosters in recipients of acellular pertussis-diphtheria-tetanus vaccine.
11/2012Evaluation of an in vitro assay system as a potential alternative to current histamine sensitization test for acellular pertussis vaccines.
1/2012A need for careful evaluation of endotoxin contents in acellular pertussis-based combination vaccines.
1/2011Non-animal replacement methods for human vaccine potency testing: state of the science and future directions.
5/2010An in vitro assay system as a potential replacement for the histamine sensitisation test for acellular pertussis based combination vaccines.
3/2009Comparison of acellular pertussis-based combination vaccines by Japanese control tests for toxicities and laboratory models for local reaction.

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Yoshinobu Horiuchi Research Topics

Disease

15Whooping Cough (Pertussis)
09/2014 - 08/2002
7Diphtheria
09/2014 - 08/2002
6Tetanus
09/2014 - 08/2002
5Poliomyelitis (Polio)
09/2014 - 03/2004
3Infections
04/2013 - 03/2004
3Body Weight (Weight, Body)
01/2012 - 01/2002
2Human Influenza (Influenza)
04/2013 - 01/2002
2Necrosis
06/2003 - 06/2002
1Weight Loss (Weight Reduction)
01/2012
1Anthrax
01/2011
1Rabies (Hydrophobia)
01/2011
1Septic Shock (Toxic Shock Syndrome)
11/2010
1Sepsis (Septicemia)
11/2010
1Weight Gain
03/2009
1Inflammation (Inflammations)
03/2009
1Communicable Diseases (Infectious Diseases)
08/2008
1Leukocytosis (Pleocytosis)
04/2007
1With Papillary Renal Neoplasia Papillary Thyroid Carcinoma
12/2004
1Haemophilus Infections
04/2004
1Paralysis (Palsy)
03/2004

Drug/Important Bio-Agent (IBA)

13VaccinesIBA
09/2014 - 01/2002
7Combined VaccinesIBA
09/2014 - 03/2009
4Diphtheria-Tetanus-acellular Pertussis Vaccines (Tripedia)FDA Link
01/2012 - 08/2002
3Histamine (Histamine Dihydrochloride)FDA Link
11/2012 - 10/2007
3EndotoxinsIBA
01/2012 - 05/2003
3Pertussis ToxinIBA
05/2010 - 12/2004
2Pertussis VaccineIBA
03/2009 - 04/2007
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
06/2003 - 06/2002
1AntigensIBA
09/2014
1Tetanus Toxoid (Vaccine, Tetanus)FDA Link
01/2014
1Diphtheria-Tetanus VaccineIBA
01/2014
1Ether (Diethyl Ether)IBA
04/2013
1Formaldehyde (Formol)FDA Link
04/2013
1InterferonsIBA
04/2013
1RNA (Ribonucleic Acid)IBA
04/2013
1Neutralizing AntibodiesIBA
04/2013
1Inactivated VaccinesIBA
01/2011
1LipopolysaccharidesIBA
11/2010
1DNA (Deoxyribonucleic Acid)IBA
04/2007
1AntibodiesIBA
03/2007
1Immunoglobulin G (IgG)IBA
03/2007
1pertactinFDA Link
12/2004
1Proteins (Proteins, Gene)FDA Link
12/2004
1Conjugate VaccinesIBA
04/2004
1Dihydrotachysterol (AT 10)IBA
03/2004
1poliovirus receptorIBA
03/2004
1Interleukin-6 (Interleukin 6)IBA
06/2003
1ToxoidsIBA
08/2002
1PyrogensIBA
01/2002